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KMID : 1149220140220020015
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Korean Journal of Oriental Medical Prescription
2014 Volume.22 No. 2 p.15 ~ p.24
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Investigation of difference of Gwakhyangjeonggi-san decoctions produced by different pressure levels and various extraction times
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Kim Jung-Hoon
Lee Na-Ri
Shin Hyeun-Kyoo
Seo Chang-Seob
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Abstract
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Objectives : Gwakhyangjeonggi-san (GJS) which consists of 13 herbal medicines has been used to treat gastrointestinal disorders caused by common cold. This study was performed to compare GJS decoctions produced using different pressure levels for various extraction times.
Methods : Decoctions were prepared by the pressure levels of 0 kgf/cm2 (non-pressurized) or 1 kgf/cm2 (pressurized) for 30?180 min. The extraction yield, total soluble solid content (TSSC), and hydrogen ion concentration (pH) were measured, and the contents of the nine marker compounds were determined using high performance liquid chromatography.
Results : The higher pressure and longer extraction time significantly increased TSSC value, while decreased the pH value. However, only extraction time affected the extraction yield of pressurized decoction. Variation of the amounts of chemical compounds was shown in pressurized and non-pressurized decoctions during extraction time. The result of regression analysis showed that pressure and extraction time can influence to extraction yield, TSSC, pH, and the content of chemical compounds.
Conclusions : This study suggests that the pressure and extraction time can significantly affect the extraction efficiency of components from GJS decoctions.
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KEYWORD
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Gwakhyangjeonggi-san, pressure, extraction time, regression analysis
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